Posted by Tom Terrific on January 23, 2004, at 8:22:28
In reply to Re: What is so special about cymbalta? » jack smith, posted by maximum-doser on January 1, 2004, at 18:53:24
Based on the posts below Scott and Bill have not been share with the drug Effexor XR which is a dual mechanism drug for serotonin and norpinephrin and has been around for several years and will have a better side-affect profile than Cymbalta. Lexapro does not normally have a dose response with the normal dose being 20 mg. Lexapro is an isomer of Celexa (basically the same drug) and is no more effective than Celexa. This is proven in THEIR package insert and in clinical trials. They are even being taken to task for false advertising by the European equiv of the FDA. Effexor has clinical trials to back up the fact that they outperform all of the SSRI's: Prozac, Paxil, Zoloft, Celexa, in treating to full remission of symptoms. Bill if you still have residual symptoms, I implore you to ask your doctor about Effexor. Good Luck
Tom
> Scott is 100% correct. There is always room for improvement. I've been on anti-depressants since 1985, and have seen tremendous and successive improvements with newer drugs. The manufacturers have done a great job of increasing the efficacy of these drugs, while simultaneously reducing their side-effects.
>
> From my personal experience, Celexa was an improvement over Prozac, and Lexapro was a HUGE improvement over Celexa. Lexapro is not only more effective, I no longer suffer from erectile dysfunction, and that is despite my taking 16 (sixteen) 20 (twenty) milligram tablets per day (a total of 320 mg)!!!
>
> I still don't have total remission, though, which is why I'm always looking forward to trying the latest FDA-approved anti-depressants.
>
> I would venture to say that much of the negativity on this board is from those who have not yet reached full remission. Negativity is a natural component of depression.
>
> Bill
> Encino, CA
>
>
> > Scott hit the nail on the head. Everytime something new comes out there are some people that are going to get better when everything else failed. More options is better. PERIOD.
> >
> > > I want something that is both safe and effective for ME. If duloxetine only helps 25% of people, and I am one of them, that's reason enough for me to want it approved. I don't know why anyone would want to prevent any new drug to be approved unless doing so somehow impacts negatively the development of still newer drugs.
> > >
> > >
> > > - Scott
poster:Tom Terrific
thread:208072
URL: http://www.dr-bob.org/babble/20040122/msgs/304546.html