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Re: Depression moclobemide narcolepsy

Posted by MARKED on January 17, 2004, at 7:35:38

In reply to Re: Depression moclobemide narcolepsy, posted by SLS on January 11, 2004, at 9:59:33

Hi Scott,
No I haven't tried any others....but i do feel based on what i've seen and heard that they can be helpful (not sure which ones off the top of my head). There is a woman in my support group that recently relapsed, and was hospitalised. I spoke with her, and she was taking some sort of RIMA recently and she improved at least 200% (perhaps it was just the thought of her not having to deal with things alone since she was back in support, or maybe it was the placebo effect)..I'll find out on Wednesday 21st Jan (i'll ask her carer the name again).

As far as things with me, i have had some thyroid blood tests and testosterone blood test (should have asked for a adrenaline one as well but forgot). Waiting to hear back about that next week (doctor feels the results will be useless).

But she (doctor) now thinks that i may have bi-polar disease. Which i was diagnosed with many years ago. (hence my constant lathargic feeling). She suggested a mood stabiliser (anti-epileptic drug) which seems to work in these situations as well.
The drug she prescribed is Tegretol (Carbamazepine).I'm studying it's effects and they seem promising, so i may not continue with moclobemide. Also they cannot be used with MOST antidepressents including RIMA's (would be lethal). So hence me hesitation to swap to another drug and go again on the merry-go-round trial. Drop off one, and wait for a response on another.

Just one more thing that I thought was interesting, she mentioned that it may be (my condition) based on the cell membranes not being as condusive of the neurotransmitters (this also seems to be common with people with: (twiches, sleeping problems, mood disorders) she stated. So i'm taking this new line of thought to think maybe it's not entirely just the bio-chemical chemicals in the brain and their balance, but how they are absorbed in the synapses etc.

Also with reading i've done on Tegretol, most people find they also are co-administering another drug to give the kick of chemical imbalance. Most drugs in the bi-polar sector are not studied that much as there is a small percentage of patients that have this disorder (wish they would read this group more often and see it's more), but they say it's like 2-5% and drug companies will not conduct haigh spending tests to release new drugs specifically for these people (expenses outway the demand). That's why anti-epileptic drugs have been used for these conditions (mood, sleep, bipolar, muscle aches, narcolepsy etc).....so again it's trial and error of getting the right combination.

> Have you tried any RIMAs other than moclobemide? Brofaromine or befloxatone?
>
> Thanks.
>
>
> - Scott


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poster:MARKED thread:281113
URL: http://www.dr-bob.org/babble/20040114/msgs/301942.html