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Re: Insomnia with Lexapro-try trazodone

Posted by zeugma on January 11, 2004, at 17:12:46

In reply to Re: Insomnia with Lexapro-try trazodone, posted by KathrynLex on January 9, 2004, at 11:17:06

most antidepressants, not just SSRI's, slow the onset of REM sleep. This is thought to be part of the antidepressant mechanism.

SSRI's, however, also "disorganize" sleep: they increase time spent in stage 1, which is the lightest, least restful stage of sleep, and block slow wave (stages 3 and 4) sleep, which is the most restful period of sleep.


IMO, this is the SSRI's single greatest drawback.


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poster:zeugma thread:296733
URL: http://www.dr-bob.org/babble/20040109/msgs/299502.html