Posted by Dr. Bob on January 10, 2004, at 17:33:47
In reply to OPIATES IN TREATMENT FOR DEPRESSION, posted by LAURA777 on January 31, 2003, at 8:55:53
> HI , i am so glad i found this site ..i do strongly believe that opiates should be considered for treatment of depression , like some of you i too have taken vicodin and percoset and have noticed massive improvement in my mood and my energy level , for instance , my mood or state is generally sad , uninterested and unmotivated,and lethargic... in fact with the questionare for depression scale , one of the questions is "did you loose interest in activities that you once found enjoyable " ? i have found nothing that has insipred my interest.. except to sleep to escape my greyness . how can i describe to you how awful this is !!! so very sad .. the main emotions that i feel are not good ones , and i have to push myself to do daily things .. i have been this way for so long that i used to think it was normal .. it started in my adolescents 12 years .i was put on prozac but this made me so flat .. then i was put on wellbutrin to augment the flatness , but here i sit with the same uninterested unmoitivated feelings .. yuk , depression runs in my family alot both sides as well as a sprinkling of bipolar, i know that i am not bipolar becasue i have never expierience mania !!! depressed is my main expierience and any good emotion is muted considerably , i know this because i pay attention to how i feel , and like some of you , when i took percoset or vicodin i actually felt much better and everything that one is supposed to do in daily life was not such a push ... what a relief this is !!!! what i want to know is why are the research companies so stuck on the serotonin and neroepinephrine , and are so frightened of the dopamine area .. hey has anyone out there ever tried amineptine ?? survector ??? it was pulled from the markets ...people who are against the use of opiates to treat depression probalby do not suffer from it the way i do .. my life sucks and the only reason i do not commit suicide is because of religious beliefs and i think it is selfish .. i would not want to hurt the ones i love soo very much .. anyway the only upside to my depression is that is has made me a deep thinker and i am compassionate.. but my life is dull for the lack of motivation and interest ,..
> i strongly believe that some of us are opiate deficient ..and it is a serious matter , i always asked myself what is everybody so excited about ?? life for me is very blah !!! and it is hard for me ... i mostly sleep because i am tired and believe it or not when i take vicodin or the like i do not feel tired , just the opposite .. i have energy and things are not a push to do ... but who is going to proscribe vicodin ?? i see a psychiatrist for the first time on feb 20 , i will let him know of all these things when i see him .. i have done quite a bit of research and have been to many of the links that are given on this forum .. there is so very much to explore and that fact that everyones brain chemistry is different makes matters much more complicated and individual ,..
> i tell you i do not want to go thru ect or use the dirty tricyclics ... i also don't want to end up like my mother who does nothing , but sleep and watch tv and is also anxious and worried all the time not to mention negitivity , the only drug she takes is xanex for angxiety..i am 38 years old and have wasted many years because of ignorance of what i have depression , i do not know wheather i am dysthymic or have retarded depression .. all i know is that i don;t want to go anywhere or do anything but i don;t want to sit here either .. This is so very hard .. i am not asking for much , i know i can;t be happy 24 7 but how about sometimes ??? how come i can't , i feel unfufilled , I would like to add that i do see a therapist and have made great strides in my self image and perceptions of things , but still i am stuck with this dryness in the area of the good feelings .. does any one understand this ?? or can anyone articulate this better ?? please please give me feedback because i feel so alone and i need validation .. i would just love to have interest , motivation .. is this is as good as it gets i am so doomed !!!!! my Father deals with his depression with alcohol , i hate alcohol it only worsens mine ....
> my research into dopaminergic drugs is slow but i do not think they target all the areas of the brain that opiates do , opiates target 4 areas of the brain and are significantly different from the stimulate drugs such as ritilan and cocaine in that they target the prefrontal cortex and nucleus accumbens , where as opiates target venteral tegmental area , nucleus accumbens , hippocampus and hypothalmus , .. i am just a lay person and have to research much more , and the only reason why i am so intense in this is because i am so so so tired of feeling this shitty ... i do not cry often even though i realte to sadness a great deal .. oh please can anyone give me some feedback it will be well appreciated , thanks , laura
poster:Dr. Bob
thread:299110
URL: http://www.dr-bob.org/babble/20040109/msgs/299110.html