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Re: can deprenyl and SSRI's be combined

Posted by SLS on January 4, 2004, at 11:06:43

In reply to can deprenyl and SSRI's be combined, posted by linkadge on January 4, 2004, at 6:24:27

> Is is safe to combine an SSRI and deprenyl ?
> Would this be something I could ask a doctor about or would they immediately say no?
>
> Linkadge


I would guess that most doctors would be resistent to the idea of concomittant administration unless they were willing to spend the time researching its feasibility. A quick look at Medline shows very few citations regarding this combination, but there are a few anecdotes reporting the occurrence of serotonin syndrome with fluoxetine and nortriptyine. One citation indicated that deprenyl was OK to combine with SSRIs except fluoxetine. How much deprenyl were you considering taking? I think it is worth taking a look at. I think I remember a few people here mixing deprenyl 5.0mg with SSRIs. You could try searching the archives.

I guess I didn't help you very much. Sorry.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&form=4&term=(deprenyl+OR+selegiline)+AND+("serotonin+syndrome"+OR+SSRI)&dispmax=200

(You might have to copy and past the URL if it word wraps).


- Scott

 

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URL: http://www.dr-bob.org/babble/20031231/msgs/296319.html