Posted by maxx44 on November 26, 2003, at 14:36:21
In reply to Re:atypical neuroleptic syndrome, posted by stjames on November 26, 2003, at 1:08:48
the fda approved zyprexa for bp-1 acute mania in 2000. search 'zyprexa approval for bipolar disorder'. no mention there of risperdal. my problems with bp1 were certainly not acute. i could make fortunes from poverty very swiftly---be stable for years and then start behaviours as flying myself and ex to hong kong and spend 30k/week shopping for every rolex, diamond, photo stuff, carpets, etc. that were clear bargains. biz-savvy crumpled, etc. i am superstitious, as many, on occassion. when i told my dr. that sometimes if a black cat crossed my path, things did seem to go awry, he called that a delusion, and such was his rational for trying zyprexa 1st. i felt something was terribly wrong and i quickly stopped after a week and then read of 'supersensitive pschycosis', where a neuroleptic may 'Produce'the very illness it was made to treat. a year later then risperdal. i informed my drs., md and phd of the intermittent fevers, loss of cognitive skills, immobility, loss of balance---they said i 'looked better' and to keep on risperdal. this was in 2001. i felt they were in error and tapered myself off over a week, only to awaken absolutely terrified of life---and adhedonic.this persisted for 2 years in spite of 300mg imipramine and 75mg librium/day. mobility or creative/cognitive functions still have not returned. i have never experienced any 'fear of life', even though also a panic disorder client. i hospitalized myself, and only then discovered i could not stoop or run. i mistakenly attributed this to lack of exercise. while hospitalized i was given trazadone for sleep and found it greatly reduced fear upon wakening. i came across the 1st mention on-line of atypical NMS in 2002. i printed the page for my md., he had never heard of it. on my last visit he had returned from a symposium and said considerable attention was devoted to ANMS. your mention of the 5ht receptors was relevant, but the lit now shows a wider range of effects. clearly my dopamine function and probably other factors currently unknown were 'hit'. we talked it over, and dextrostat 5mg/3 times/day was scripted to get me moving. adhedonia persists, but i am briskly walking 5 miles/day. i was 56 at risperdal onset. for the 2 years after cessation i spent hours sitting with my left leg crossed on a hard-bottomed chair. now i seem to have an arthritic left hip---this has not been confirmed, but the pain is chronic and now i'm 59. this is certainly not a risperdal result, other than from its production of low motor activity and my subsequent sitting pattern. my bp daughter, prior to symptoms, was a berkley regent scholar---only 24 of such/year---she does have acute delusional manic episodes, she was repeatedly raped at age 9---i feel this a factor in her severity. orange county has her on paxil and zyprexa daily. this concerns me from experience. she's 26, probably more resilient than i, but i fear her cognitive skills, which led to the highest level of academic status, may be lost. not to mention the other long-term risks you note. in 25 years of biz i was rarely litagous, the fla. 2 year statute is gone, so i am not attempting to build a case---i simply want her safe, and me recovered. over years i've seen few shrinks that see clients, non-stop daily, that return home eager to spend their free time continuing research. i feel the pace of the drug cos. marketing, and slow recognition of relatively rare reactions requires ceaseless study. thank you.
poster:maxx44
thread:283350
URL: http://www.dr-bob.org/babble/20031126/msgs/284134.html