Posted by SLS on November 23, 2003, at 9:57:20
In reply to Re: Lamictal- dosage recommendations for depression? » SLS, posted by poop'd-out on November 22, 2003, at 23:50:15
> > > I also take Zoloft, Neurontin and Tegretol, which I know affects the lamictal dosage. I may just be on too many meds I don't know. Having trouble typing this even. Any input would be soo appreciated!
> >
> >
> > The interactions between these drugs are rather complicated. How is the level of Lamictal affected by the other drugs?
> >
> >
> > - Scott
>
>
> Hi Scott,
>
> The only thing that I know is that tegretol supposedly does the opposite of what depakote does. Instead of doubling the amount of lamictal in your system(depakote), the tegretol halves the amount of lamictal. But, the lamictal also increases the amounts of zoloft and tegretol, by how much I don't know.
> This is just from literature that I have read and from what my Doc confirms.
>
> Beth
Hi Beth.I can't find anything that describes an increase of either Tegretol or Zoloft by Lamictal. However, there have been reports of Zoloft increasing levels of Lamictal to the point of toxicity. I have a chart that indicates the following:
lamotrigine - reduced by carbamazepine; increased by sertraline
gabapentin - no changes
sertraline - increased by carbamazepine
carbamazepine - increased by sertraline
- Scott
poster:SLS
thread:99395
URL: http://www.dr-bob.org/babble/20031121/msgs/282794.html