Posted by zeugma on November 19, 2003, at 18:43:41
In reply to Re: IS THIS REALLY ACURATE?? Ratio of Sero / NE ??????, posted by SLS on November 19, 2003, at 14:31:22
With imipramine the 5-HT/NE ratio is going to be variable based on differences in the way the drug is metabolized. Some people are slow metabolizers and get more of the serotonergetic parent drug, others will process it quickly and will get more of the NE-specific metabolite. TCA's in general are among the most variably metabolized drugs. That is one reason determining blood levels can be inportant when taking them.
poster:zeugma
thread:280491
URL: http://www.dr-bob.org/babble/20031116/msgs/281399.html