Posted by Flipsactown on November 13, 2003, at 7:37:58
In reply to Has anyone had luck restarting pooped out AD?, posted by Ilene on November 6, 2003, at 14:10:08
Hello Ilene,
I also had dramatic results with desipramine, only I took it with prozac. It is suppose to increase the effects of prozac. This combo worked for 7 years for me and then pooped out. I had alternated between prozac and zoloft with the desipramine. If you are suffering from unipolar depression, then you need to look into taking lamictal which I am currently taking with prozac and in 6 weeks I had the dramatic results that I had before with the prozac. Desipramine was not added until the prozac pooped out after 2 years. Go to this link and it has good information about treatment resistant depression, www.bipolarworld.net/Phelps/ph_2003/ph1016.htm
Good Luck,
Flipsactown> I am about to re-start desipramine (I think the trade name is Norpramin), which was the first AD I ever took, about 15 years ago. I stopped taking it when I was trying for my 2nd kid, and it stopped working when I started taking it again.
>
> Is there any chance it will work after giving it a 13-yr rest? It had unpleasant side effects, but it worked as well as anything else.
>
> The plan is to augment it with an anti-psychotic, probably risperidone (Risperdal), if necessary, to stop the intense circular ruminations.
>
> The other plan is to wait until duloxetine (Cymbalta) is on the market or try venlaxafine (Effexor) again. I *hated* Effexor, but I was taking it with a handful of other drugs, including bupropion (Wellbutrin), which might have added to the twitchiness and all-around unpleasantness.
>
> The pdoc thinks I need an SNRI. I'm not going to argue with her. At this point it's all hit or miss.
>
> Any experiences here?
>
> BTW, I've been trying tiagabine (Gabatril), and it keeps me awake at night! The pdoc was thought it was going to be the best thing since sliced bread. Back to neurontin. I need my sleep.
>
> Ilene
poster:Flipsactown
thread:277206
URL: http://www.dr-bob.org/babble/20031111/msgs/279313.html