Posted by Ame Sans Vie on October 31, 2003, at 7:57:51
In reply to Re: elizabeth about dosing on opiates/ anyone, posted by Chuckie on October 30, 2003, at 15:10:05
Perhaps OxyContin *is* a bit much to ask for, even from a doctor who is not opiophobic. I find that some extended-release forms (especially Avinza) work at least as well as the hillbilly heroin for depression -- and Avinza is a 1 dose/24-hour pill, so that would save you the trouble of taking extra pills and going on the now-it's-working/now-it's-not rollercoaster provided by twice daily dosing. Two 120mg capsules in the morning worked great for me while I was on it. I never found MS-Contin to be very effective, and Duragesic transdermal (fentanyl patches) were rather depressing for me -- surprising considering fentanyl's "China white" reputation on the street. I found codeine far too weak, of course, as I did hydrocodone (needed 300mg/50mg respectively to feel depression relief). Ultram (mixed mu-opioid agonist, 5-HT/NE reuptake inhibitor) is a wonderful drug and I personally find it better for depression than either morphine or oxycodone. Gotta take DLPA and an NMDA antagonist with your opioids though... anything you can do to prevent tolerance. I take DLPA 2,250mg/day and dextromethorphan 60mg/day to prevent amphetamine tolerance, and have used the same cocktail to prevent Ultram tolerance -- works like a charm.
Finally, just wanted to note that there is also a form of buprenorphine sublingual tablets available without the naloxone, called Subutex.
Michael
poster:Ame Sans Vie
thread:84007
URL: http://www.dr-bob.org/babble/20031030/msgs/275195.html