Posted by DayByDay on September 26, 2003, at 16:15:54
In reply to Re: Re to Jasmine: Cannabiod Receptors, posted by Caleb462 on September 26, 2003, at 13:13:55
> Like a previous poster said, there are specific receptors in the brain (cannabanoid receptors) that THC attaches to. Cannabanoid receptors are not well understood, in comparison to some other brain receptors at least.
>
> However, I do know that THC has been shown to inhibit the release of the neurotransmitters acetylcholine and norepinephrine. It also has conflicting effects on GABA (potentiates GABA in some area's of the brain while inhibiting GABA release in other areas). I believe dopamine release does occur from THC as well, but probably on a much smaller scale than other addictive drugs.Thanks for the information Caleb462, it was new
to me. My question is what the practical effects
of these changes are?Are they minor or major and how relavant are they?
What function has acetylcholine?
Even though it doesnīt seem like an spelling error Iīll ask you just in case: do you mean norephedrine (noradrenaline) by norepinephrine,
or is it my spelling thatīs wrong.
Anyway if it is norepinephrine then what fuction does it have?Then finally the GABA effects how would they interfere with other GABA drugs like anticonvulsants?
I would like to say thing I would like to say that may be of importance for MJ-smokers - although MJ helps many people with depression there is new research suggesting it may cause depression aswell which could mean some MJ-smokers are treating a depression that was initially caused by MJ.
If you like to read more about this go to
the NEW SCIENTIST homepage and check out their
marijuana section - they have lotīs of good information and are objective reporting about
both possible positive and negative sides of MJ as well as the political/legal issues related to it.And finally NikkiT2 said:
"I don't really drink alcohol (occasionally, maybe once every couple of months I'll have a couple of drinks, and maybe get drunk once a year).."
Iīm exactly like you - very occasionaly Iīll have a beer or two or maybe even a third if its a
suitable occasion. As far as being party-drunk
it happens only but not necessarly at special occasions such as someones birthday or new-years eve.Whether I smoke occasionally or chronically attribute my mild alcohol consumtion to the smoking. Alcohol can be as a ok relaxant in small amounts but being drunk (although alcohol technically is capable of being the most intoxicating of the all traditional drugs) really isnīt that fun expept in exeptional occasions. I any case smoking is 10 times nicer. Besides if I am heavily stoned I canīt drink that much either because I just got too tired to enjoy being awake.
Most of the stoners Iīve spoke to agrees with
the fact that cannabis consumtion decreases
their alcohol consumtion and I personally think
that a legalisation would have this effect at
the part of population that would smoke, giving
them a (generally) much safer and nicer alternative.
I donīt know if their has been any research done
on this in the Netherlands for instance.
poster:DayByDay
thread:263379
URL: http://www.dr-bob.org/babble/20030923/msgs/263569.html