Posted by serenitypeace on September 13, 2003, at 13:07:08
In reply to Re: All the AD work for 3 weeks only! Why? » serenitypeace, posted by bookgurl99 on September 13, 2003, at 11:26:41
> Serenity --
>
> gosh, I knew a friend who had similar side effects. And I have to say, long-term use of SSRI's makes a lot of people _feel_ depressed, supposedly because homeostasis sets in and the brain lowers the amount of dopamine along with the amount of serotonin receptors. Maybe your brain is just _really good_ at getting to this point.
>
> It sounds like you might have to trick your system, either with lower doses of meds -- I've heard of people who lower doses work for better than higher doses -- or, probably, by taking something dopaminergic alone _or_ with an ssri.
>
> I've heard of dopamine-enhancing meds Strattera, Wellbutrin, etc., being added to an SSRI, or even being taken alone to combat depression. Have you tried that?
>Hello bookgurl99,
Your theory of receptors adaptation is quite interesting. I read something similar once which explained why drug addicts need increasing amounts of narcotics. The funny thing is that I had the exact same response with fish oils. A dose of 4 grams EPA+DHA/day responded for 25 days before the beneficial effects started to vanish. About the Wellbutrin, my doc put me on it while I was on Effexor; It did no do much. Maybe it would help with my present cocktail, who knows?
Thanks for the insight
poster:serenitypeace
thread:259603
URL: http://www.dr-bob.org/babble/20030912/msgs/259658.html