Posted by Ame Sans Vie on September 5, 2003, at 17:49:33
In reply to Re: Dopamine and Serotonin » Ame Sans Vie, posted by Francesco on September 5, 2003, at 17:25:18
> Thanks for answering me ...
No prob.
> Which are the dopaminergic meds ? Wellbutrin and stims ?
Wellbutrin and methylphenidate are both dopaminergic and noradrenergic; amphetamines affect DA, NE, and 5HT. Beyond that, the only purely dopaminergic meds are those for Parkinson's disease, mostly dopamine agonists such as pramipexole, ropinirole, cabergoline, bromocriptine, and amantadine. Deprenyl is an inhibitor of MAO-B and thus increases concentration of DA in the brain... then there are the precursors -- levodopa/carbidopa, tyrosine, and phenylalanine. Too bad amineptine isn't so easy to get ahold of these days...
> Is that the reason why some folks are treated with SSRIs and Wellbutrin ?
In many cases, yes, the Wellbutrin is added on to the SSRI to eliminate or decrease the sexual side effects and apathy. In fact, "Cel-Well" is a term that originated in California, I believe, to refer to a combination of Celexa and Wellbutrin, which is apparently very popular.
Stimulants and DA agonists are also very good augmenting and anti-side-effect agents combined with 5HT reuptake inhibitors.
> In your opinion can this work in the LONG TERM ?
Well, anything's possible... provided you manage to avoid the poop-out phenomenon, that is.
poster:Ame Sans Vie
thread:257332
URL: http://www.dr-bob.org/babble/20030902/msgs/257396.html