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Re: Are the MAOIs the big-guns or what? Avoidant pers. » Francesco

Posted by Ame Sans Vie on September 5, 2003, at 8:23:24

In reply to Re: Are the MAOIs the big-guns or what? Avoidant pers. » jonh kimble, posted by Francesco on September 5, 2003, at 6:35:30

Though I don't know the doses of the trifluoperazine/tranylcipromine in the medication you're describing, I'd have to assume that the neuroleptic would dull the effects of the MAOI. Tranylcipromine is said to be among the more stimulating MAOIs (all we have here in the U.S. to compare it to are phenelzine and selegiline), presumably due to active amphetamine metabolites, as well as the MAO inhibition factor. I would think that this has quite a bit to do with increased/improved/altered functioning of the dopaminergic system, and antipsychotics are dopamine antagonists... not to mention that the old, "dirty" neuroleptics like Stelazine, Thorazine, Mellaril, et al carry with them a host of horrible side effects.

But anyway, do you have any idea what the dose of each drug in the pill is? Or whether there are any other MAOIs available in Italy? I'm sure the tranylcipromine/trifluoperazine combo isn't the only one... there are so many of them.


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poster:Ame Sans Vie thread:256953
URL: http://www.dr-bob.org/babble/20030902/msgs/257232.html