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Re: new Paxil alternative

Posted by Nohope on September 4, 2003, at 4:14:08

In reply to Re: new Paxil alternative, posted by CamW. on September 3, 2003, at 1:13:39

> Nohope - If you look at the three-dimensional configurations of many psychotropics in vivo, they resemble common antihistamines (eg. promethazine). It is just the side groups (-R) that make all the difference.

Does this mean that receptors for different neurotransmitters have very similar 'structures' - if that is a meaningful term? What are the implications for drug development? (does this make development easier or harder?)
Hopefully someone comes up with a different fundamental structure that forms the basis of a new family of medications - that is effective for us treatment resistant folk.


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