Posted by McPac on August 30, 2003, at 2:37:08
In reply to Re: Remeron, posted by Caleb462 on August 28, 2003, at 15:24:29
Brother Caleb and ALL of you other dudes and dudettes that would love to take a crack at this.
sooo glad you mentioned this:
"Yes, but SSRIs increase serotonin in the brain in a matter of hours, whereas it takes up to 12 weeks
for OCD symptoms to be reduced. Get what I'm saying?">>>>>>>>>>> My brain is definitely not normal or average..perhaps it's not even human...but I have had, on more than one occassion, SEVERE depression and SEVERE ocd SIGNIFICANTLY improved in extremely short periods of time. I posted regarding this phenomenon some time back and did get a few responses from posters saying the same thing (not many but there were some, one VERY much like me). In one instance, incredibly severe dep/ocd (when I was much younger), that was DRAMATICALLY improved (almost completely wiped out) in a few short days upon beginning medication. SAME thing happened again years later. I have had times when I was very depressed (lousy, physical/biochemical depression, truly depressed, I'm not talking merely "blue" about something that happened, and I have felt noticeably (even markedly) better after one pill within mere hours! Of course I have to keep taking meds to sustain that or else the depressed feeling would immediately return again. (And NO, I'm NOT saying that 1 pill and I'm perfectly fine, I'm saying 1 pill and I can notice a REAL improvement (2,3 or 4 pills and there is DRAMATIC change)..not EVERY time does this happen but on many occassions this HAS happened) Anybody's reaction here is no doubt, "oh you weren't really depressed....that's not possible"....3 such instances occurred while I was being hospitalized!!! I WAS in TERRIBLE shape!! HOW in the heck did I get a REAL mood lift, a REAL change, from 1 pill? It's NOT placebo, it's REAL! Sometimes, after I get that incredible initial response, my mood will fall back to depressed again and then I will have to keep taking the pill for quite a long while until I feel well again.....I also recall times where I got a very good initial "pop" from a medicine (a VERY quick positive response for the first few days) that then faded and then had to wait quite a while for the med to once again resume working.....but I have gotten INCREDIBLY quick responses on many occassions from 1 single dose......I know it might defy logic or science but it's totally true...but, often times, this same fast reponse WON'T happen; for instance, other times I may take the same pill (when I'm feeling the same way as before) and I WON'T get that unbelievable response, in fact I won't get any response at all...so this incredible phenomenon happens often with me but it is NOT a given at all. I'd LOVE to hear an explanation....I think it's some kind of super-sensitivity kind of thing....I AM very med-sensitive...the way I see it (seriously) is that if my brain is SO sensitive to all of the negative effects of a med (side effects) and to stimuli in general then it should also be equally sensitive to the positive effects. I just see it as a super-sensitive brain (receptors?), which is why I often get such incredibly fast results from meds. I'd really, really like an explanation though as this has baffled me for years. One other possible explanation (theory) I have is that on the occassions when my dep/ocd has gotten VERY bad, perhaps the dep/ocd is triggered by terrible, dreadful anxiety (severe nervousness) and that the meds act quickly on my nerves, settling them down first..and because my nerves settle down, I then feel much, much better just as a result of THAT..and once my nerves settle down that the dep/ocd then begins to settle down...so perhaps it's that quick nerve-settling effect of the meds that is the reason why the dep/ocd symptoms diminish relatively shortly thereafter.......I actually think that theory, or a combo of the two I've mentioned, are close to the reason. But I'd REALLY, REALLY love to know how this is possible, as even my former doctors didn't know what to think and were totally baffled.
poster:McPac
thread:251624
URL: http://www.dr-bob.org/babble/20030828/msgs/255551.html