Posted by Ame Sans Vie on August 5, 2003, at 16:56:12
My meds are definitely staying the way they are, but I've long been curious about these two medications, especially in treating anxiety. Rilutek (riluzole) is a med for amyotrophic lateral sclerosis which inhibits the reuptake of GABA-A and GABA-B (unlike that godforsaken Gabitril, which just targets GABA-B) and possesses anticonvulsant and hypnotic properties. Sabril (vigabatrin/gamma-vinyl-GABA) inhibits GABA-transaminase, the enzyme that is to GABA what MAOI is to dopamine, serotonin, norepinephrine, etc. Nardil also inhibits GABA-T, which could largely account for its anxiolytic action.
Now that I think of it, though either of these drugs alone could be great, *combining* the two could be wonderful!
So anyone have any experiences? Or information? I'm gonna go do some more research on this myself. Thanks!
poster:Ame Sans Vie
thread:248342
URL: http://www.dr-bob.org/babble/20030802/msgs/248342.html