Posted by BekkaH on July 28, 2003, at 22:17:28
In reply to Zoloft/Coumadin, posted by JaneJ68 on July 28, 2003, at 19:16:48
Hi Jane,
You are absolutely right. Your doctor should know that serotonin affects platelet aggregation. Over the past few years, I have come across several articles about the risk of bleeding, especially GI (gastrointestinal) bleeding, in patients who are on SSRI's (serotonin reuptake inhibitors) like Zoloft. That risk is heightened for patients on anticoagulants such as Coumadin and Heparin. I am not a physician, but if I were you, I would rather lower the Zoloft dosage than the Coumadin. In fact, I would probably taper off of the Zoloft and replace it with an antianxiety agent such as low dose Klonopin, at least until your medical condition is stabilized. You should NOT tamper with your Coumadin dose by yourself. Don't lower the anticoagulant dose without discussing this with a KNOWLEDGEABLE physician.
Bekka
poster:BekkaH
thread:246281
URL: http://www.dr-bob.org/babble/20030728/msgs/246336.html