Posted by Jack Smith on July 21, 2003, at 17:26:53
In reply to Re: » Jack Smith, posted by jrbecker on July 18, 2003, at 10:41:55
> > http://www.injuryboard.com/view.cfm/ID=752
>
> unbelievable
>Isn't that crazy?
> Yes, NK-1 antagonists work on substance P - and are considered the same thing.Do you have any clue when some of these may be available for depression? I understand that the one now available for chemotherapy-induced nausea is priced extremely high and may be giving the company an incentive to hold its approval for depression.
> Right now, there has been no movement on it. Ocinaplon [by DOV] is like pagoclone, but has done a lot better in testing thus far. It is entering Phase III trials next month, but will not be on the market for at least two whole years.
>At least. That sucks.
> Take pregabalin for instance. Not a particularly great anxiety drug on its own (cumbersome side effects at higer doses, questionable efficacy when stacked up against other anx drug profiles)
So, I take it you don't believe the pregabalin hype? Do you think its efficacy will be similar to neurontin given that it seems to be a modified version of neurontin.
> is xanax xr a much better drug or is it just a slight tweak on the orginal form?
>I'd say it's a slight, but significant tweak on the original form. I think if you didn't like xanax in the first place, you probably wouldn't like the xr. One big thing for me is there is no crash that I used to get from regular xanax. It seems a little less sedating and has a more subtle effect. I have not however decided to use it daily yet. I may in the future. Just not sure I want to go down that road yet, though I definitely get a noticable AD effect.
JACK
poster:Jack Smith
thread:242854
URL: http://www.dr-bob.org/babble/20030718/msgs/244022.html