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HELP! Which is more effective way to take LITHIUM

Posted by Janelle on July 21, 2003, at 16:28:21

I'm on 600 mg of Lithium Carbonate a day, which is the highest dose I can tolerate (well blood level wise) and I was talking all 600 mg at night. Then the next day I had bad tremors to the point where I could barely write, and I have nice handwriting! :-)

I asked my pdoc if it's possible to have s/e like the tremors without being in the *toxic* range on a blood test, and she said yes, it sure is possible.

My sister suggested that I ask my pdoc about splitting the dose into 300 mg in the am and 300 mg in the pm. So I did, and pdoc's immediate response was that this might make the tremors worse (I should have asked why, but didn't). But she encouraged me to "experiment" and try it for a week or two.

So far, results are MIXED! Some days, daytime tremors are bad and others they aren't. What I have noticed is that I feel more *mellow* and patient on the split dose (can a mere 300 mg in the am really have such an effect?).

Then at night when I take the other 300 mg I now have difficult falling asleep (I had less difficulty when I took the 600mg at night - I'm on a bunch of other meds as well)

Does anyone here know which is more effective/recommended for taking Lithium Carbonate - should a person divide the dose or take it all at once?


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poster:Janelle thread:244002
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