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Re: seizure-like jolt on effexor? » bookgurl99

Posted by noa on July 17, 2003, at 17:52:55

In reply to seizure-like jolt on effexor?, posted by bookgurl99 on July 16, 2003, at 8:28:27

Yes, it is called myoclonus. I get that with Effexor, as I did with Paxil. I believe it is due to serotonin stimulating the 5ht2 receptors in the muscles.

To counter it, I take Serzone with the Effexor. Serzone blocks postsynaptic 5ht2 receptors, as I understand it (my neuro understanding is pretty limited). I also take a benzo (ativan) to counter similar SEs--ie, akithisia/restless legs, though this is a bit different than the myoclonus. Some people take Klonopin or Mirapex for leg movements.


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