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Re: again with the questions, Ame Sans Vie » Henryo

Posted by Ame Sans Vie on July 5, 2003, at 14:59:58

In reply to again with the questions, Ame Sans Vie, posted by Henryo on July 5, 2003, at 4:16:09

> How did you start Mirapex? Does one have to ease into it? How much each day, for how long? Have you noticed any side effects?
>
> I know I'm pestering you, but you're the Mirapex man and I need to know all this stuff. Any other Mirapex advice? Thanks

You're not pestering me at all--I've been away from the computer a few days and didn't see your original post.

I started Mirapex at a dose of 0.5mg three times a day (much higher than the 125ug t.i.d. that's recommended for starting out). I quickly ramped my dose up to 4.5mg/day within a week. No problems encountered, except some pesky nausea that I was able to keep under control with ginger and occasional Dramamine.

The recommended titration schedule I'm seeing lately is:

0.125mg t.i.d. the first week
0.250mg t.i.d. the second week
Then raise by 0.5mg t.i.d. each week

The only problematic side effect I notice (now that the initial transient nausea has passed) is sleepiness during mid-day. I've been able to correct this with a combination product containing Korean ginseng 250mg, bee pollen 100mg, gotu kola leaf 100mg, L-carnitine complex 100mg, royal jelly 25mg, inosine 5mg, and octacosanol 50ug, once daily. Another worthwhile approach would be Provigil, but this stuff was $2/bottle at Dollar General, lol.

Anything else you need to know, feel free to ask!


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