Posted by Shawn. T. on July 3, 2003, at 19:38:30
In reply to Re: Methadone, posted by Ed O`Flaherty on July 3, 2003, at 17:43:25
Here are a few links about buprenorphine and alpha-2-adrenoceptor agonists (like clonidine). For more quality information, you may want to search PubMed using a search string like "methadone withdrawal" or methadone AND withdrawal. I think that a combination of an alpha-2 agonist with buprenorphine might be an interesting strategy; you might discuss that with your doctor. I have known people that had some luck with alpha-2 agonists; they seem to help with the sympathetic rebound (increase in norepinephrine neuron activity) associated with withdrawal.
Buprenorphine: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12831383&dopt=Abstracthttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8201637&dopt=Abstract
Alpha-2 agonists:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12804419&dopt=AbstractShawn
poster:Shawn. T.
thread:238912
URL: http://www.dr-bob.org/babble/20030701/msgs/239073.html