Posted by noa on June 27, 2003, at 23:38:56
In reply to Re: Why dopaminergic for RLS but not for akathisia? » MB, posted by Ritch on June 27, 2003, at 23:20:51
The very first time I ever took an antidepressant was kind of like that. I took only a first dose (1/3 of the target dose--I think I took 25 mg) of amytriptaline (sp.?)and had simultaneous hyperactivity/agitation (akithisia?) and extreme sedation. Not a good combo. Couldn't keep my eyes open but couldn't keep still--felt like I was going to jump out of my skin. I had had similar, but milder, reactions to antihistamines before this, but nothing ever quite like this. It was the first and last time I took a TCA. I ended up going to the ER because of how distressing it was. I was so sedated that my speech was slurred and I couldn't walk straight but also totally climbing the walls and jumping out of my skin at the same time.
Sometimes, I get a similar feeling, in a milder form, after I've taken my Serzone and lorazepam, while waiting for the sedating effect to kick in enough to go to sleep. I have the "itchy" resltessness but also the droopy eyelids. It is not pleasant, but since it is short lived until the sedation wins the battle, and it is much milder than what I had with the amytriptaline, I can tolerate it.
Of course, it is now many years later and I am much more used to meds, so that kind of extreme reaction and sensitivity to meds that I had back then probably wouldn't happen anymore.
poster:noa
thread:237227
URL: http://www.dr-bob.org/babble/20030624/msgs/237618.html