Posted by shrimp on June 14, 2003, at 11:15:53
In reply to Re: nardil fainting wellbutrin, posted by indivmed on June 13, 2003, at 21:09:20
> My experience has been somewhat similar when it comes to an MAOI (for me, Parnate) and Wellbutrin. I will say that as a bipolar patient, it might have been a little overkill. I turned pretty hypomanic and at times during the day, would feel like I would after a 4-day speed binge (without sleep)--I would REALLY ADD, almost twitchy, and felt like I would fall out at any moment.
>
> Anyway, I added the Wellbutrin to the Parnate because I was exhausted on the Parnate. I've heard that Parnate is supposed to be stimulating...does this happen after a month or so of being on it? Also, Parnate has caused me hypertension instead of hypotension--hypertension of late (which Wellbutrin does NOT exacerbate)...anyone with this experience?
>
> Has anyone tried Provigil instead of Wellbutrin? I'm just interested in the Wellbutrin because it affects dopamine which the MAO can't touch due to the MAOI. I know that Provigil is stimulating, but by a completely different mechanism...
>
> I did add Depakote to the Wellbutrin and Parnate and this smooted things out a little--kept me from getting too wild :).
>
> Rick
>
Rick,
I have taken Parnate, and it made me that tired as well, but at the same time i was shaky. I would crash particularly hard around 4 pm. I've always had the sleepy lethargic depression, so my p-doc kept me on 400mg of W and added the Nardil. I was at 45, last week upped to 60mg.
I became very agitated and anxious about a week later, so we have decided to lower the W to 300mg., as i felt like i was twitching uncontrollably and having mini seizures at night, which hopefully will slow down as the W leaves my system. I did try Provigil, didn't do anything. I can say that since i've been on the Nardil for about 5 weeks, the sleepiness has remissed somewhat, and that may be due to the wellbutrin i am taking with it. I had bad hypotension on Parnate, it's bad on the Nardil as well. If i were you, i would try adding a low dose of W to the Parnate, if your p-doc will let you. I was not getting results from anything, zoloft, parnate, paxil, etc. and this combination, after going through about a month of miserable side effects, finally seems to be working, outside of the speedy felling on 300mg. In my experience, dopaminergic agents have been key to clearing up some of my mental fog, so i think that the Wellbutrin is a good addition. Have you tried Nardil? Don't know if you can augment Parnate with it. Also on the Parnate, extreme cold sensitivity, bloating, fainting, insomnia. May i ask how many mg. of W and Parnate are you on, and how long you have been taking them? Then i can give you some more information on what to expect not expect. I am atypical, and you are bipolar, so take that into account when comparing our experiences. If you have any questions, please let me know.
Shrimp
poster:shrimp
thread:232905
URL: http://www.dr-bob.org/babble/20030614/msgs/233938.html