Posted by Paulie on June 12, 2003, at 21:30:03
In reply to Re: MAOI and Soy Milk-Paulie, posted by Maxime on June 12, 2003, at 19:52:33
I don't believe that I am misinforming anyone. Yes, I know the old lists are outdated without much scientific evidence. As I mentioned before, five lists that I have list soy milk as UNRESTRICTED(as much as you want). However, if a person is getting a reaction to a certain food while on an MAOI it is recommended to avoid that food even if it is not on the list. That is common sense. I got a reaction to soy protein powder which was not on the list I had. It was not aged. It would be foolish for me to continue ingesting it though. There is even a reference to soy milk on a PB's MAOI DIET (short list). If you disagree with this then maybe Dr. Bob should change it. It says:
"SOY FOODS are controversial: one sample of soy sauce was reported to have quite a lot of tyramine in it, but there aren't any documented interactions. My experience has been that a little bit of soy sauce is okay. I would avoid other soy products, such as soy milk and tofu. The Taiwanese dish called "stinky tofu" is
probably right out. < g >"http://dr-bob.org/tips/maoi.html
This IS the opinion of one poster, but HAS been placed under PB's information for an MAOI diet.
As far as tyramine content needed to obtain a reaction I have based my infomation on scientific studies. There is even one here at PB.
It says:Walker, Scott E. MScPhm. Shulman, Kenneth I. MD, SM, FRCP(C). Tailor, Sandra A.N. PharmD. Gardner, David BScPhm. Tyramine Content of Previously Restricted Foods in Monoamine Oxidase Inhibitor Diets. Journal of Clinical Psychopharmacology. 16(5):383-388, October 1996"
"It has been clearly demonstrated that individuals who are taking MAOIs are more sensitive to the pressor effects of tyramine. [15] A critical issue in dietary restriction relates to the amount of tyramine that will produce an increase in blood pressure. Both Blackwell and Mabbitt [16] as well as Horowitz and associates [17] have observed increases in blood pressure with the ingestion of only 6 mg of tyramine. However, Blackwell and Mabbitt [16] were unable to reproduce these results on rechallenge with 6 mg in the same subject. Bieck and Antonin [15] demonstrated that an 8-mg oral dose of tyramine is sufficient to increase systolic pressure by 30 mm Hg in 50% of subjects receiving tranylcypromine. However, they also demonstrated a wide intra-individual variation in responses in some patients that may be due to variability in both the rate and extent of absorption. Furthermore, many foods have been reported to contain variable amounts of other pressor agents [18-21] that may also increase blood pressure, possibly contributing to variable response. [15,16] Therefore, we have used a conservative upper limit of 6 mg of tyramine as a guideline for safe ingestion. This is identical to the limit that we have used previously. [7,8,11]
http://www.dr-bob.org/babble/20010804/msgs/73614.html
Who's misinforming?
Paul
poster:Paulie
thread:233470
URL: http://www.dr-bob.org/babble/20030609/msgs/233564.html