Posted by Ritch on June 9, 2003, at 10:21:58
In reply to Re: My endocrinologist says Seroquel lowers thyroid » Snoozy, posted by jerrympls on June 9, 2003, at 0:19:33
> > Hi -
> >
> > I copied this from the medline page on Seroquel:
> >
> > Other medical problems?
> > The presence of other medical problems may affect the use of quetiapine. Make sure you tell your doctor if you have any other medical problems, especially:
> > Alzheimer's disease?Quetiapine may cause problems with swallowing, which may increase the chance of pneumonia; also, the chance of seizures may be increased
> > Breast cancer, or history of or
> >
> > >>>Underactive thyroid?Quetiapine may make these conditions worse
> >
> >
> > Here's where you can find the whole page:
> >
> > http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/203124.html
> >
> > Have you had your thyroid checked recently?
>
> Yeah, TSH was 7.67 and T4 was 0.7. I see my endocrinologist on Tuesday.
>
Jerry, I copied this from the prescribing info for Seroquel:Hypothyroidism: Clinical trials with SEROQUEL demonstrated a dose-related decrease in total and free thyroxine (T4) of approximately 20% at the higher end of the therapeutic dose range that was evident early on during treatment and maintained without adaptation or progression during more chronic therapy. Generally, these changes were of no clinical significance and TSH was unchanged in most patients, but about 0.4% (10/2386) of SEROQUEL patients did experience TSH increases. Six of the patients with TSH increases needed replacement thyroid treatment.
poster:Ritch
thread:232512
URL: http://www.dr-bob.org/babble/20030609/msgs/232604.html