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Effexor and serotonin » mattdds

Posted by kalyb on June 9, 2003, at 9:03:16

In reply to Re: Too much EFFEXOR for too long? » Taylor123, posted by mattdds on June 8, 2003, at 18:41:11

> You see at low doses Effexor has only serotonergic effects (only works on serotonin).
>
> But at higher doses, Effexor works on both norepinephrine and serotonin. So this is actually a strategy used by doctors. My understanding is that this is the *main* advantage of Effexor in the first place.

I'm wondering about this.....

I'm on 75mg/day of normal Effexor (not XR) which would probably be considered a low dose.

Within 2 days of starting it (I was started on 75mg) my anxiety disappeared completely like someone had pulled a switch, and has stayed "off" ever since. (It's been just over 4 weeks now).

Now logically, there must be something else at work there other than an effect on seratonin.

What it might be, I don't know, but surely extra seratonin on its own isn't enough to have that kind of effect on anxiety... especially not my kind! If that were the case then other SSRI's such as Prozac, Paroxetine and Celexa would have worked for me.... they didn't, and in fact made my anxiety worse when I was taking them.

Any thoughts?

Kalyb xx


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