Posted by djmmm on June 8, 2003, at 8:24:26
In reply to Re: Not nessarily , posted by Questionmark on June 7, 2003, at 4:42:23
> > Some people can experience very strange effects from combining SSRI's with stimulant drugs. Many people note a reaction to smoking+SSRI's.
> >
> > Since the serotogenic and dopamanergic systems generally work inversly, stimulating both at once can be dangerous, especially since Ephedrine can be hazardous alone. Doing so, can also increase the likelyhood of serotonin syndrome.
> >
> > I would take caution, or at lease take a small trial dose combination before delving right in.
> >
> > Linkadge
>
> Well, you may have a good point.
> Two clarifications though: 1) i'm pretty sure ephedrine does not directly affect DA systems at all-- it's just an adrenergic agonist.
> 2) Ephedrine is not hazardous alone if the person is using reasonable amounts-- thats my opinion at least.The stimulating effects from ephedrine are blocked by dopamine antagonists that effect D1 and D2, so the dopamine system is involved, but its primary effect is on the alpha-adrenergic receptors...I would suggest pseudoephedrine, but ephedrine is typically safe, but like every drug, if taken in excess, or in combination with other stimulants, you increase the risk of side-effects (cardio and otherwise)
poster:djmmm
thread:232094
URL: http://www.dr-bob.org/babble/20030604/msgs/232344.html