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Re: RITCH: the TWO Depakotes ... » Janelle

Posted by Ritch on June 7, 2003, at 0:33:53

In reply to RITCH: the TWO Depakotes ... » Ritch, posted by Janelle on June 6, 2003, at 18:53:44

> Okay, I've checked into the matter(!) and have come up with the fact that EC (Enteric Coated) for easier digestion/absorption are DIFFERENT formulation than ER, Extended (slow) Release and that one should NOT take a 125mg EC with a 250mg ER to get a total of 375 mg.
>
> My pdoc bumped me up from ONE 250 mg ER (the white boring ones, not smelling like vanilla) to THREE of these three times a day for a total of 750 mg.
>
> Even with the divided doses which he said should help with the side effects I was getting with taking it all at once, I'm STILL getting side effects (typical for me; I'm extremely sensitive to meds almost to the point of becoming treatment resistant I fear).
>
> Anyway, what dose (total) of Depakote are you on, and I hope you are NOT combining the EC with the ER??? Just wondering ...
>
> Thanks.


I guess our pdocs are of two different opinions. Mine says divalproex sodium is divalproex sodium no matter how you cover it up with whatever coatings. I think your pdoc doesn't want to jack around with little titration steps and wants you on PLENTY of Depakote-just a hunch :) ! I'm just taking ONE of those white boring pills every day (250mg). Just an FYI, but in the prescribing info for Depakote ER it says you can take two 500mg ER tabs together at one time per day.


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