Re: how do you get serotonin syndrome with 2 SSRIs?

Posted by Caleb462 on May 26, 2003, at 22:32:20

In reply to how do you get serotonin syndrome with 2 SSRIs?, posted by cybercafe on May 26, 2003, at 21:33:08

> i'm wondering if Effexor XR 75 mg + Celexa 20 mg is safe
Sounds pretty safe to me, though of course I'm not a doctor.
I actually don't think you CAN get serotonin syndrome from combining two SSRIs... or if you can, it's likely rare. SSRIs, at their theraputic dosages, block 60-80% of the serotonin transporters in the brain. Raising the dosage, or adding another SSRI, would simply raise that level to 100% - and this should not cause serotonin syndrome. I could of course be wrong, though.

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how do you get serotonin syndrome with 2 SSRIs? cybercafe 5/26/03
Re: how do you get serotonin syndrome with 2 SSRIs? Caleb462 5/26/03
Re: how do you get serotonin syndrome with 2 SSRIs? djmmm 5/27/03
Re: how do you get serotonin syndrome with 2 SSRIs? cybercafe 5/29/03

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