Posted by Tony P on May 23, 2003, at 2:25:53
In reply to Re: On Serzone. Add SAM-E and/or 5-HTP?, posted by Caleb462 on May 20, 2003, at 12:27:59
> As for 5-HTP, it's useless. A scam. It does not cross the blood-brain barrier.It may be useless, but in my experience it has SOME effect. Perhaps it disturbs a metabolic equilibrium. I tried taking it for insomnia while I was on AD's (Wellbutrin and/or Serzone), instead got much worse insomnia, and what I've now come to recognize as a mild case of Serotonin Syndrome (i.e. excess).
My old Merck lists 5-HTP as a serotonin precursor; the question is, where does it "precurse"? Which side of the blood/brainn barrier? Does circulating serotonin affect receptor activity? All pharmacologists/biochemists on deck - bring me up to date here!
poster:Tony P
thread:227860
URL: http://www.dr-bob.org/babble/20030520/msgs/228514.html