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SLEEP meds update

Posted by jrbecker on May 21, 2003, at 13:13:09

A few new sleep meds will be hitting the market within a year's time. All are non-benzo's like Sonata or Ambien. However, these new compounds are claiming more effectiveness in treating transient as well as chronic insomnia. Further improvement is seen in addressing not only problems with sleep initiation but also sleep maintenance (staying asleep).

Indiplon from Neurocrine (IR and MR formulations)
Phase III complete, planning NDA in early '04
http://www.neurocrine.com/ar02/indiplon.html
http://www.biospace.com/news_story.cfm?StoryID=12713520&full=1


Eszopiclone (ESTORRA) from Sepracor
NDA submitted to FDA in 5/03
http://www.sepracor.com/pharm/
http://www.biospace.com/news_story.cfm?StoryID=12722520&full=1


Zolpidem MR (Ambien sustained-release version)
Phase III trials wrapping up. NDA planned for early '04.


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poster:jrbecker thread:228087
URL: http://www.dr-bob.org/babble/20030520/msgs/228087.html