Posted by SLS on May 16, 2003, at 10:07:44
In reply to trying 3rd time - re med second trial:, posted by Janelle on May 15, 2003, at 22:02:03
Hi Janelle.
> I just want to know if going off a med (in this case Buspar) for a few days, then going back on would be considered skipped doses or an actual second trial (because I read on here that second trials of the same med often don't work)? Any info greatly appreciated.
I agree with the others that missing a few days of dosing of a psychotropic would not endanger your response to it. However, I would have to disagree with them regarding your question about a reduced efficacy of previously successful trials of the same drug. It does happen, and it happens often enough to want to take the phenomenon into consideration when deciding whether or not to discontinue medication. This seems to apply most to the SSRI antidepressants. It can also happen with lithium. I can't comment on the frequency with which this happens. I don't know. It happens often enough to have landed me on Psycho-Babble. 13 years ago, a doctor had me discontinue a very successful treatment of Parnate 60mg + desipramine 150mg. After I relapsed two months later, he decided to give the newly-approved Prozac a try. I guess it was a new toy. It didn't work. Neither did the next few things he decided to try. Now, the previously successful combination no longer works, even when dosages were doubled.
- Scott
poster:SLS
thread:226476
URL: http://www.dr-bob.org/babble/20030514/msgs/227025.html