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Re: Neurontin Effects? » Tiffany1203

Posted by medlib on May 16, 2003, at 6:45:22

In reply to Neurontin Effects?, posted by Tiffany1203 on May 16, 2003, at 0:08:38

Hi Tiffany--

I'm a bit unclear about why you're taking nortriptyline and why your PCP took you off of it. Nortrip can *cause* peripheral neuropathy; it can also cause elevated liver enzymes and heart palpitations. But, since you were off of it for 8 wks, you should be able to place the onset of various symptoms and the liver function test in a timeline which includes that 8 wk hiatus and be able to infer at least a little about which drug may be causing what. Nortrip has also been linked with disorientation, somnolence and dizziness, as well.

Neurontin is not metabolized in the body (it's excreted unchanged in the urine), so it's a little difficult to see how it could cause liver problems, but the drug lit mentions post marketing reports of liver dysfunction (causation not established). Elevated liver enzymes in the absence of palpable liver inflamation does suggest a biochemical rather than infectious cause; but high values should be taken seriously, whatever their etiology.

Here's a link to a site with comprehensive information on drugs:
http://www.rxlist.com/interact.htm

Hope this helps.---medlib


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