Posted by Jack Smith on May 12, 2003, at 16:23:19
In reply to Re: Please, need info from Prozac users/former users!, posted by jrbecker on May 10, 2003, at 10:48:27
JR, you are a wealth of information!
> Prozac is by far my favorite of the SSRIs. I am quite sensitive to most ADs, so my optimum dosage was probably 10mg. At this level, the sedation was minimal.
I thought you preferred Celexa, my favorite SSRI that pooped out. Hmm, I wonder if Prozac would be good for me. What is your opinion of Prozac-zyprexa combo or would you say too many risks?
>
>It acts on GABA too, so perhaps this is why it's great for anxiety for some people -- I really never found prozac all that activating since I took it at such low doses.I've never found ANY drug activating, including Wellbutrin and adrafinil (those did not sedate me though). Never tried stimulants. Do you think a stimulant would do well with Effexor? What about a stimulant to counter the beginning sedation of Remeron?
>
> ANnother thing to note about prozac is that it is an antagonist at the 5HT2C site, which is quite the opposite effect from all the other SSRIs. As a result, there is an increase in dopaminergic/NE activity in the prefrontal cortex. It's my belief that this is the reason prozac is a better drug for treating anhedonia than the rest of the SSRIs.
>That's interesting but don't you think Prozac would have less sexual side effects than the rest of the ssri's because of its 5ht2c antagonism?? I always thought it was one of the worst ssri's in this regard.
Thanks,
JACK
poster:Jack Smith
thread:225329
URL: http://www.dr-bob.org/babble/20030505/msgs/226145.html