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Re: Remeron rocks for treatment-resistant unipolar » jrbecker

Posted by SLS on May 11, 2003, at 9:24:35

In reply to Re: Remeron rocks for treatment-resistant unipolar, posted by jrbecker on May 11, 2003, at 2:38:03

Hi JB.

> remeron takes a bit of time to get comfortable with. It's probably the first med where I waited over a month and found eventual positive effects finally kick-in. This is a med with long-term payoff.

Thanks. It is good to know that.

> I really think you should give remeron another go, maybe even monotherapeutically. From reading your posts, it sounds like you have a high tolerance level for most meds. Maybe spend less time at 30mg and try to bump up to 45 mg as soon as possible.

I like that idea.

I am a bit shy about Remeron, although I have never been on it for more that a few days. When I was a patient at the NIMH, they had me take a drug known as idazoxan. It made my depression significantly worse, and I had to endure it for several months. Idazoxan, like Remeron, blocks NE alpha-2 receptors. When I felt worse 1-2 days after beginning Remeron, I attributed it to this shared property. Of course, it is sometimes silly to think we can predict with certainty what these chemicals will do within the milieu of our complex neurobiology.

Did Remeron make you feel worse in the beginning?


- Scott

 

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