Posted by Ron Hill on May 9, 2003, at 2:32:59
In reply to Ron Hill: Enada TMG?, posted by KarenB on May 7, 2003, at 12:54:15
Hi Karen,
> I went to my health food store and found TMG in a powder form(5g) and caps(750g). Nothing close to 250mg. Where are you finding this dosage?
I use my handy-dandy pill cutter to hack up the 500 mg tablets (Life Extension brand) into smaller portions.
Or, alternatively, I use my handy-dandy razor blade to slice capsules of a product called "SAMe Kick Start" into my approximate dose size. The granules inside the capsules have a strong taste, so I mix the dose in a small amount of juice and drink it down. SAMe Kick Start is marketed by Living Earth and each capsule contains 695 mg of TMG, 185 mg of DMG, 250 mg of L-methionine, 15 mg of B-6, 800 mcg of folic acid, and 200 mg of B-12. I'm taking the Kick Start 'cause I already had it lying around. After it’s gone, I plan to use the much more affordable TMG.
> I started NADH but seem to be aggitated more than usual in the afternoon - I am rapid cycling Bipolar.Sounds like you might be taking too much. How much are you taking? I love this stuff, but I can only take 2.5 mg once per week or else I get VERY IRRITABLE. Even at the once a week dosing frequency, it induces some irritability on the day that I take it. What mood stabilizer(s) are you taking and at what dosage(s)? What other meds and dosages? Do you feel more motivated when you take the Enada NADH? What symptoms are you trying to treat with the Enada NADH?
> Maybe the TMG would help with this?
No, probably not. At least not directly. TMG has an activating kind of action and, therefore, will most likely not reduce the irritability. In fact, for a given dosage of Enada NADH, the addition of TMG might make the irritability worse. The benefit I find in adding TMG is that it seems to extend the time period of effectiveness for the Enada NADH. In other words, without the TMG, a 2.5 mg dose of Enada NADH loses its effectiveness after about four days. But with TMG, it lasts a full week. Therefore, TMG indirectly reduces my irritability by reducing my Enada NADH dosing frequency.
Having said all this, irritability is still a problem that I have not fully resolved. I'm thinking about adding a trial of Neurontin to see if that would help.
> Also, have you ever suffered from migraines and has this aggravated those at all?
No, I have no experience with this. Have you ever tried Depakote to treat the migraines? I can't imagine the pain of having migraines on top of all the other generic bipolar woes.
-- Ron
poster:Ron Hill
thread:224878
URL: http://www.dr-bob.org/babble/20030505/msgs/225319.html