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seroquel+sedation » Janelle

Posted by MattD on April 22, 2003, at 0:15:03

In reply to SNOOZY! You're not gonna believe THIS -- , posted by Janelle on April 19, 2003, at 20:45:41

It still could be the seroquel. It is sedating, for sure, even at 50mg. And it can last through the next day. It's not all about half-life; one also has to look at how protein-bound the drug is, as well as the active metabolites the drug has and their effects.

But with a large cocktail, it's often a combo of things.

As far as BuSpar goes, anecdotally it doesn't work all that well for anxiety. It does do well, often, in augmenting antidepressants, especially SSRIs.

Matt

> I did the quick 'n dirty Internet search to find out the half-life of Seroquel and guess where it led me to - I made a circle right back here to PB! I got a hit that made mention of a really good website that is a chart full of drug info, alphabetical by brand or generic name.
>
> According to this site Seroquel has a half-life of 6 hours. Sounds kinda short? Another site said 7 hours.
>
> I forget if half life depends on the dose level (I don't think it does) -- the chart says Seroquel typical dose is 300-500 mg. But I'm not taking it for the labeled reasons so that doesn't concern me.
>
> If 6 hours is considered a short-half life, then it ain't the Seroquel that's keeping me drowsy all day!
>
> FYI - the website with the great chart is:
>
> http://sl.schofield3.home.att.net/medicine/psychiatric_drugs_chart.htm.


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URL: http://www.dr-bob.org/babble/20030417/msgs/221343.html