Posted by jrbecker on April 11, 2003, at 12:35:43
In reply to Re: Remeron Questions » maryhelen, posted by Ron Hill on April 10, 2003, at 9:47:55
Mary Helen:
in terms of the tolerance effect or other-wise colloquialized "poop-out" effect, some do report less effectiveness when re-initiating a medication for a second time. Whether this is due to a tolerance build-up to the drug's effect is uncertain. However, I do believe that this effect is overestimated and that most people do respond efficaciously to the same drug if it was successful the first time around.
I don't think this should discrouage you from trying remeron again. Remeron is a fabulous drug for those who are refractory with the SSRIs. In many ways, it acts completely opposite to their effects. Most people I know that are on it have found a comfortable dosage window where they report less sedation than when on an SSRI. My doc even reports some cases where people have experienced less weight gain on remeron than when on an SSRI. It's all individual differences. Don't get me wrong, parnate is a great drug, but a lot more cumbersome b/c of it side effects. If you were having some success with remeron, I would definitely suggest a re-trial of it and try to push the dosage up as high as you can. And maybe down the line, you can look to adjunct with something else to start to figure out a weight loss plan. I can probably add a few suggestions to that as well. Good luck.
JB
poster:jrbecker
thread:217889
URL: http://www.dr-bob.org/babble/20030411/msgs/218518.html