Posted by Ron Hill on April 4, 2003, at 18:34:12
In reply to soooooo unmotivated. seroquel?, posted by jonh kimble on April 4, 2003, at 11:40:47
> Hi I have big time problems with motivation, anhedonia, social withdrawl and inability to sustain a conversation etc... (i believe low dopamine is to blame) and this is just the normal me.
Jon,
I had the same symptoms as you and I agree that it is a dopamine problem. The good news is that an OTC product called Enada NADH (coenzyme 1) is doing a remarkable job in treating these symptoms (which I refer to as the atypical depressive phase of my BPII disorder). This is the tenth week of my Enada NADH trial so it is too early for me to report on the long-term efficacy.
For the finer details, read one of my prior posts at the following link:
http://www.dr-bob.org/babble/20030306/msgs/206934.html
As an update to this previous post, I currently take 2.5 mg every fourth day (Take 2.5 mg on day one; skip days two, three, and four; take 2.5 mg on day five). As stated in my previous post, 10 mg/day was a good dose during the acute treatment phase.
Since you are BP II, I'd ditch the AP and get on a first-line moodstabilizer (Depakote or lithium). I don't like the TD risk of an AP, but that's just me. Why does your pdoc have you on an AP instead of a MS?
If you have questions, just ask. I'd bet dollars-to-donuts that Enada NADH will snap you out of your atypical depression (low motivation, etc) within hours of taking the supplement. However, what I don't know is if it will cause irritability for you or if it will poop-out over time. I hope it helps long-term.
-- RonHere are some of the links discussing Enada NADH:
http://www.healthwell.com/hnbreakthroughs/mar98/nadh.cfm?path=hw
http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8101444&form=6&db=m&Dopt=b
http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9247090&form=6&db=m&Dopt=b
http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9013405&form=6&db=m&Dopt=b
http://www.wholehealthmd.com/refshelf/substances_view/1,1525,10047,00.html#Cautions
http://www.nadh.com/site7/SYSact20.htm#Top
http://www.nadh.com/site7/RSdprs05.htm#Top
http://www.smart-drugs.com/article-JamesSouth-NADH.htm
http://www.nadh-priceinfo.org/
http://qualitycounts.com/fpnadh.html
http://www.immunesupport.com/library/showarticle.cfm/id/3118/T/Both/
http://www.immunesupport.com/library/powersearch2.cfm (Note: enter “NADH” as keyword)
poster:Ron Hill
thread:216188
URL: http://www.dr-bob.org/babble/20030402/msgs/216295.html