Posted by Michael Bell on March 22, 2003, at 12:45:15
In reply to Re: Almost there..., posted by falconman on March 22, 2003, at 11:00:47
> Hi,
> and thanks for all the updates.
>
> I envy your success with picamilon. I have been taking it for 2 weeks now at 300mg/day, and the SP hasn't changed at all. Infact recently i've been more scared and shakey socially then I've been for a while. I conclude that this supplement doesn't evan touch my anxiety problem. This seems strange as other GABA drugs can really help. eg Klonopin.
> I had high hopes for this supplement-hey ho!!
> take care
> Falcon
Falcon,Many of the descriptions I have read say this is a very potent drug. It shoots GABA straight to the brain. I think 300 mg a day is too high of a dose, and I say this from experience. All of the sites say to take 150 mg/day (50 mg in 3 doses) for anxiety. Doses above that cause STIMULATION, which believe me is not the effect that you want if you have primary social phobia.
In my experience - I started out taking 100mg or 200 mg a day. I liked the effects, so I figured 300 mg a day would be better. Wrong! I was extremely wired and woke up one morning with a terrible case of GABA-induced anxiety. I felt extremely weak, had some tingling in the extremities, and the very thought of stepping foot outside seemed overwhelming. In my worst days of SP, I don't think I've ever felt as bad as I felt that day. Basically, I was extremely overstimulated. !!!Remember, GABA has both inhibitory and excitatory functions!!! You may be thinking, how much difference could 150mg a day make with respect to psychological effects, but most drugs have very different effects at different levels.
I have not yet been able to find a site that sells pills smaller than 100 mg. Therefore right now I take 100 mg a day, and that is perfect for me. No sedation, no hyperstimulation, no anxiety. Anything above that is too much - I get overstimulated, then very fatigued. Also, for about 7-10 days after starting this supplement, I had anxiety for about 1 hr after each dose, then I kicked in with a vengeance and I felt great. Now there is very little fluctuation and absolutely no anxiety. I've been on it for about a month, and all's well.
I'll continue to update every 2 weeks and report any changes.
Good luck!
poster:Michael Bell
thread:211414
URL: http://www.dr-bob.org/babble/20030319/msgs/211456.html