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From Dr. Bowden: Lamictal, Bp1 and Hypom.

Posted by Dr. Bob on March 11, 2003, at 15:01:15

In reply to Bowden: Lamictal, Bp1 and Hypom., posted by elbee on March 7, 2003, at 9:06:50

Dear Elbee,

No long term studies other than open data are available regarding Lamictal in combination with other medications for bipolar I patients. It is highly likely that the combination with lithium, or Depakote will work. It is possible, but less clear, that combination with antipsychotic drugs (Seroquel, Zyprexa, Risperdal) will work. The likely benefit from the Lamictal will be less depressive symptoms long term. Because Lamictal is routinely combined with other anticonvulsants in the treatment of epilepsy, we have good evidence from those studies indicating that Lamictal can be combined safely with Depakote, Topamax, Keppra, and Zonegran. There is good evidence to indicate that no hypomania will be caused by Lamictal. However, it does not treat hypomania.

For most persons who have difficulty getting to sleep or staying asleep, a drug such as Ambien or Prosom is the best aid. However, these drugs if taken in excess can reduce the sharpness of one's memory.

If a drug reduces alertness in the morning, the only real remedy is to try taking it somewhat earlier in the evening, or, alternatively, reducing the dose of the drug.

Charles L. Bowden, M.D.


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poster:Dr. Bob thread:205791
URL: http://www.dr-bob.org/babble/20030310/msgs/208128.html