Posted by Jack Smith on March 4, 2003, at 16:37:07
In reply to Re: EXP'NCED P'BABLRS PLS ADVISE: Parnate or Effexor? , posted by SLS on March 4, 2003, at 6:53:05
> I think Mitch (Ritch) has focused on an important point - you ARE responsive to SSRIs. Effexor (venlafaxine) is sort of a like a combination of SSRI + TCA. That you are resonsive to SSRIs leads me to believe that Effexor has a pretty good chance of working without poop-out (tachyphylaxis). A recent study of over 2000 patients demonstrated that Effexor has a somewhat higher rate of producing an antidepressant response than SSRIs, and has a much lower rate of pooping-out than SSRIs (probably similar to TCA).
>Scott, Ritch (Mitch?) or others,
I tend to agree with you guys that Effexor is probably the better alternative at this stage in the game. BUT do you guys think that the fact that an ssri worked and then pooped out means that other ssri's won't work (granted Effexor is an snri as well as an ssri) or do you think it means that another ssri has a better chance of working since I have previously responded well to one? I know that everyone is different but what are your thoughts/opinions? By the way, Mitch, the reason why I am not thinking of prozac is that its half life is too long so if I did switch to an MAOI, I'd probably have to wait quite a while.
Thanks in advance,
JACK
poster:Jack Smith
thread:205524
URL: http://www.dr-bob.org/babble/20030301/msgs/205890.html