Posted by Ritch on March 2, 2003, at 9:48:42
In reply to Re: Ritch, posted by Rainbowlight on March 1, 2003, at 22:21:11
Ahhhhhh, day one back on Remeron, I feel like a new person! Amazing stuff! No obsessing, stressing or sleepiness. I'm in heaven! And last night I slept like a log with just the Remeron, no sleep med. Geez, I hope this works! Still drinking tons of water, lol! Bought some chewing gum to try to kill the sugar craving the Remeron always brings late at night. Now I just have to remember not to eat the WHOLE pack of gum at one sitting. The other night I ate two WHOLE packs of lifesavers before bed. How sick is that? Makes me cringe! What was I thinking? I have a major sweet tooth. I will bump up 15 mgs every 3 days until I reach 45. Hopefully all will go well. How are you? Sleeping any better? I hope so!
> Ritch, please read the LAST post from "Patients" under the post "Remeron, please help I can't eat" (I tried to paste it here but it wouldn't work). I think this is what my doctor is talking about, about the higher dose, what do you think?OH you mean this one:
As for Remeron, at lower doses it actually causes an increase in appetite as a result of blocking histamine receptors. This is also what causes the extreme sleepiness at lower doses. Remeron causes the serotonin system to get turned down and the norepinephrine system to be turned up, but this occurs at higher doses. You shouldn't have to worry about the norepinephrine system if you only take it at low doses. One reason doctors increase Remeron qucikly after starting a patient on it is to counteract the drowsiness and the increase in appetite that commonly occurs at the low dose end. Increasing the dose stimulates norepinephrine which counteracts these effects. The lower dose end is better for those that suffer from extreme anxiety or that need help with sleep. You are already at the high end for Remeron. The usual start up dose is 15 mg a day, and depending upon response, increased to 45 mg a day.
From what I understand Remeron "saturates" the histamine receptors at just about any dose. Dose increases kickin the noradrenergic effects as mentioned, which would likely begin to supress appetite. Obviously you have got a Remeron "circuit" readymade for your brain! I've got some major temper problems and it makes them really bad, so I can't take the stuff. I liked Remeron's regulation of my IBS symptoms better than anything else (and of course sleep). I would just like to take a selective serotonin antagonist that had a short half-life at bedtime to help sleep and cool my gut.
poster:Ritch
thread:204786
URL: http://www.dr-bob.org/babble/20030301/msgs/205251.html