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Re: TCAs » not exactly

Posted by zeugma on February 18, 2003, at 20:04:56

In reply to Re: TCAs » zeugma, posted by not exactly on February 18, 2003, at 13:21:56

> > I definitely have a serious problem with overstimulation.
>
> Is the problem _endogenous_ overstimulation or _exogenous_ overstimulation? I certainly don't have endogenous overstimulation - quite the opposite - since stimulant meds help me. But I definitely have the exogenous overstimulation problem - I'm mood-reactive and hypersensitive to external sources of irritation. I found that Neurontin helped me with that. Have you ever tried Neurontin? It might help with your social anxiety and insomnia.

Exogeneous overstimulation. The few times I've been in a video arcade prove that. More seriously, I pick up on others' feelings quickly, this is both a good thing and a bad thing. If people around me start acting weird, I get freaked out too. Jobs where I have to deal with the public are always a problem for this reason. It's hard for me to maintain my calm around people when I feel so easily influenced by their moods.
>
> > upping the dose of nortrip to 45 mg from 40
>
> ??? That sounds like an almost negligible increment. Why not 50, since it's a standard dose? (So is 25 if you want b.i.d.)

I started nortrip at 20 mg, immediately became irritable and quit my job- as I've posted here a while ago, this was a good thing in the long run, but was unsettling at the time. It took more than a month to get up to 30 mg between the irritability and orthostatic hypotension. 40 then was too much- went to 35 instead and spent a month or two there. Went up to 40, end of November. My experience has been that 10 mg increments cause too much hypotension. 5 mg will get me another 5 mg from a standard dose. Plus I've gained a few pounds on this stuff, so I think it's time to bump it up a little. (weight gain is healthy for me.)
>
> > I think Buspar might be a good adjunct for you too. It does have a dopaminergic effect so it might help the anhedonia.
>
> That's the intriguing part. The meds that have helped me the most have been those with some dopamine-bosting effect (Mirapex, Wellbutrin, Ritalin, Dexedrine, Selegiline). I will see my pdoc in about a week and hope to get a Buspar Rx then.


Buspar is said to be good for movement disorders and maybe Parkinson's too. It seems to have helped with my bruxism.
>
> > When I started taking 10 mg a day (5 in the morning/ 5 at night) I felt the effect right away.
>
> What effect did you notice? Just a reduction in anxiety, or were there other benefits? And how soon is "right away"? Within 24 hours?
>
Within 24 hours. I was noticeably calmer and had an easier time socializing. Consistent with its dopaminergic effect, too, I noticed that it improved libido and sexual sensation.
> - Bob
> z


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