Posted by viridis on February 16, 2003, at 18:59:57
In reply to About Wellbutrin XR - Questions, posted by jparsell82 on February 14, 2003, at 12:56:37
I didn't like WB at all, and had many side effects, so I quit it after 2 months. However, I have anxiety problems, and WB can exacerbate these (it certainly did for me). For others it can be very helpful (I know one person who found it a great AD, and another who completely freaked out and thought she was having a heart attack the first time she took it).
Re: dosage: 300 mg seems pretty typical, usually titrated up from 150 mg over a week or so. The maximum is generally considered to be 450 mg, although there are exceptions.
Oh, and regarding sexual side effects: I had lots of other side effects, but none in that area. I've heard other anecdotal reports of it increasing libido, and it's sometimes used to offset the sexual s/e of SSRIs.
The mechanism of action isn't fully understood (as usual) but it seems to involve increased concentration of norepinephrine ("adrenalin") in certain synapses.
Good luck!
poster:viridis
thread:200413
URL: http://www.dr-bob.org/babble/20030214/msgs/200997.html