Posted by Ritch on February 8, 2003, at 9:40:21
In reply to dexedrine spansules vs. adderall, posted by Peter on February 7, 2003, at 18:32:19
> Hi all:
> Just came back from pdoc. Mood has been all over the place this week;. He doesn't want to prescribe me another antidepressant as of yet, since he really thinks the lamictal will help my SP and cycling as we titrate it. I'm now on 75mg, going to 100mg. But he did say I should replace my 30mg adderall (10mg x3) with 30mg dexedrine spansules (2x5mg tid). The reason for this is, as I had already heard, the dexedrine doesn't have the l-isomer, only the d, which many have said is 'smoother' on their mood. So, I got it filled, took 2x5mg, and then noticed on the insert that it says 'take last dose 12-14hrs. before bed'. It's already 7:30pm! I'm used to taking my 3rd adderall dose this time, and my pdoc said the dex spansules are NOT longer acting than normal adderall (in other words, not like adderall XR). Is this true? Why does it say that? Anyone have experience with dexedrine spansules? Are they in fact 'smoother' then adderall and do they last the same amount of time? Thanks as always,
> PeterIn my experience with immediate-release dexedrine it was considerably "smoother" (mentally-much less anxiety-provoking) than Adderall. However spansules will be probably a little bit more uneven than Adderall as far as the release of the drug is concerned. It is supposed to release half of its medicine all at once and then the other half gradually, so you may notice a quicker "kick" at first and a little waviness in its release later on-but you are taking it 3x daily so that might not be an issue. I had much less elevated heart-rate and blood pressure on dexedrine. The l-isomer in Adderall has a half-life of about 11 hrs or so (from what I've read anyhow) so it shouldn't be taken too close to bedtime either. So your pdoc is right about the dex spansules not being any longer acting than regular Adderall. It is probably more of a deal about Adderall *not* mentioning avoidance of late-day dosing.
poster:Ritch
thread:140031
URL: http://www.dr-bob.org/babble/20030208/msgs/140134.html