Posted by Larry Hoover on January 5, 2003, at 16:11:35
In reply to Re: Larry H.- Question about L-Arginine » Larry Hoover, posted by catmint on January 5, 2003, at 14:39:15
> >I'm not familiar with arginine supplementation. I'd be happy to investigate it for you, if you give me a little bit of the rationale. I got 25,000 hits in Medline, and I'm not sure what lead to follow.
>
> L-ARGININE is an essential amino acid necessary for the formation of nitric oxide, the body's key signaling molecule for starting and maintaining arousal.
>
> Larry, this is what I found from a product called Argin-max. Maybe you know something about nitric oxide?
>
> Other ingredients include ginseng and gingko biloba.
>
> IF l-arginine does in fact treat SD, then I wonder if it would counteract the sexual side effects of some of the SSRIs?
>
> Just wondering.
>
> Thanks,
> AmyOh, *that* SD. I was confused by the ambiguity of the initials.
Ordinarily, I'd be inclined to suggest that NO is a bad guy in depression, as it contributes to oxidative stress, something that probably is already elevated.
There was one study on that particular product, probably published by someone who has a monetary interest in the product (I'm somewhat cynical). However, it seemed to work, though it didn't say if the SD was related to antidepressants.
J Sex Marital Ther 2001 Oct-Dec;27(5):541-9
A double-blind placebo-controlled study of ArginMax, a nutritional supplement for enhancement of female sexual function.Ito TY, Trant AS, Polan ML.
University of Hawaii, School of Medicine, Honolulu, Hawaii, USA.
This study was open to women over the age of 21 years with an interest in improving their sexual function. Of the 77 participants, 34 received ArginMax and 43 received a placebo. ArginMax for Women is a proprietary nutritional supplement consisting of extracts of ginseng, ginkgo, and damiana, L-arginine, multivitamins, and minerals. After 4 weeks, 73.5% of the ArginMax group improved in satisfaction with their overall sex life, compared with 37.2% of the placebo group (p < 0.01). Notable improvements were also observed in sexual desire, reduction of vaginal dryness, frequency of sexual intercourse and orgasm, and clitoral sensation. No significant side effects were noted.
poster:Larry Hoover
thread:134143
URL: http://www.dr-bob.org/babble/20021230/msgs/134636.html