Re: TCA discontinuation???

Posted by oracle on December 16, 2002, at 17:34:04

In reply to Re: TCA discontinuation???, posted by SLS on December 16, 2002, at 6:20:07

> > Given the length of action & long half life
> > I would not expect missing a dose or taking a little less to make much difference the next day,
> > with TCA's.
>
> For some people, nortriptyline can have a very narrow therapeutic window. If you take too much, you can lose the antidepressant effect. I don't know if this is one of those instances, but I had a similar experience with the drug.
>
>
> - Scott
But we are just talking about one day or one dose'es worth of change. Again, given the half-life of this med I would not expect this to effect the "narrow therapeutic window" provided
the change was just one day. At least this is my experience, having been on AD since 1984. In 84
most all we had was TCA's and I found the long half life ment I could miss a day with no ill effect. I never noticed a missed dose.

Thread

TCA discontinuation??? johnj 12/15/02
Why lexapro? » johnj JaneB 12/15/02
Re: TCA discontinuation??? oracle 12/16/02
Re: TCA discontinuation??? SLS 12/16/02
Re: Why lexapro? » JaneB johnj 12/16/02
Re: TCA discontinuation??? » SLS johnj 12/16/02
Re: TCA discontinuation??? » johnj Ritch 12/16/02
Re: TCA discontinuation??? oracle 12/16/02
Re: TCA discontinuation??? SLS 12/16/02
Re: TCA discontinuation??? oracle 12/16/02
Re: TCA discontinuation??? SLS 12/17/02
Re: TCA discontinuation??? » oracle johnj 12/17/02
Re: TCA discontinuation??? oracle 12/17/02

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